David Sinclair has a lot to offer in this book. The subject matter is urgent, and worth reading if you have an interest in optimizing your health for longevity. There are a lot of moments in the book, however, that tend to drift away from the health aspect of the book. In one chapter, he speaks entirely of the politics of longer lives, which I’d argue has little to do with why I and others would have picked up the book in the first place. The sentiment is worth reading, just not why I chose to read the book. Sinclair tries to offer some of the context necessary to understand the science of longevity, but without a background in biology, it tends to get really hard to understand. It isn’t his fault, just a fact of the subject matter. Overall, really good stuff. Definitely a must read for health nerds.

I estimate that, so far, I have listened to the audio version of this book (50 +/- 15) times.

Nice to think there are many positives in the future.

I rarely find nonfiction to be a page-turner, but this David Sinclair book happens to be a shining exception. The book flows from the past, present, and future of defying aging without missing a beat. The complex topics are explained elegantly without being overly simplistic. Not to mention the joy of peering over the shoulders of a world-renowned expert. An excellent read is a bonus considering the truthful information on living a healthier, longer life. I plan to implement some of the suggestions in this book myself.

This book it's a must read. Inspiring, Beautiful, eloquent!. Science explain dummies proof. The information it's so thorough, helpful and enriching.

What otherwise was an interesting and optimistic tome until Chapter eight morphed into something else...

This book takes a fresh look at aging and seeks to label it as a health condition. The primary thesis is: if we solve the general problem of aging - which the author says is easier to solve than cancer - much of the other specific ailments and diseases that plague society in old age will decline or go away entirely. Evidence is presented of successful and repeated research that is lengthening the life of mice up to 40% with simple supplements available today. Some brave people are taking these supplements and seeing unbelievable improvements in health. This book is awesome. I’ll be reading it again. And I’ll be sharing it with family and friends. It will be added to the list of books I reference as I seek a healthier and longer lifespan for myself and loved ones.

Useless information on world practical tips. At least tell us more than, “eat less”, “take metformin”.